Madhu Powle has worked as an artist for the Indian comic book collection 'Amar Chitra Katha', a series of stories from Indian mythology, history, folklore, and culture. The series, started in 1967 by author and editor Anant Pai, also included pieces by artists including Dilip Kadam, Souren Roy, Chandrakant D. Rane, Geoffrey Fowler, Ram Waeerkar, and Pratap Mullick. The "Harsha" issue has been drawn by Powle.